Based on the content of your post I think that some of us here might be mistakenly thinking that these trials are blinded trials,
which they are not,
they are in fact open label trials, with 2 design purposes one of safety and the other of establishing the most effective dose rate for the following trial which will at that time be of the type (blinded etc) that you have suggested.
As this is an open label trial the management are free to disclose or on the other hand not disclose information until when appropiate.
fp
IMU
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